A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational ...
Enzymes act as catalysts within the living cells and are made up of proteins. All chemical reactions occurring in a living organism are dependent on the catalytic actions of enzymes, and this is why ...
Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life – how enzymes are ...
Peroxidases are enzymes that break down hydrogen peroxide in organisms. Since their discovery in 1998, the electron source of "peroxiredoxin 6-type" peroxidases for this reaction remained unclear. The ...
Man prides himself upon his growing mastery over nature, but in the ultimate biochemical analysis nature remains the master of man. With their most sophisticated laboratory glassware and corrosive ...
Saxitoxin—a compound made by marine microbes that can contaminate shellfish—is a toxin so potent that minute quantities can prove deadly. Its mode of action means that less toxic versions have ...
Evolution has crafted thousands of enzymes that are efficient catalysts for a plethora of reactions. Human attempts at enzyme design trail far behind, but may benefit from exploiting evolutionary ...
Pericyclic reactions, which involve concerted electron movement and a cyclic transition state, have long been a part of the synthetic chemist’s tool box. But finding enzymes that catalyze such ...