Human protein kinases constitute a large superfamily of about 500 genes, historically classified into subfamilies based on phylogenetic relationship. However, many kinases remain unclassified.

New computer simulations that model every atom of a protein as it folds into its final three-dimensional form support the existence of a recently identified type of protein misfolding. Proteins must ...

Recently identified and long-lasting type of protein misfolding — non-native entanglements — observed in all-atom protein folding simulations. Representative misfolded conformations of the small ...

Antimicrobial peptides (AMPs) are essential components of the innate immune system in humans and other organisms, exhibiting potent activity against a broad spectrum of pathogens. Their potential ...