Massachusetts Institute of Technology (MIT), engineers developed a new liver tissue model to help reveal the stages of liver regeneration in hopes to help those individuals with liver disease, ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

A 3D liver model was engineered by a team of researchers, that accurately replicates the connection between liver cells (hepatocytes) and scarring cells (stellate cells) in the condition of fibrosis.

A team at Baylor College of Medicine and other institutions has developed a novel mouse model that reproduces many key features of human non-alcoholic fatty liver disease (NAFLD), a little-understood ...

The liver is the only internal organ that can regenerate itself. Remarkably, even if 70 percent of the liver is removed, its tissue can regrow into a full-sized organ within a matter of months. By ...

Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

Scientists have developed a functional human hepatic tissue in a mouse host. The human hepatic tissue, in the mice, is composed of human hepatocytes and non-parenchymal cells (NPCs) including human ...

Periportal assembloid, with the three component cell types visualized: cholangiocytes in pink, portal fibroblasts in green, and hepatocyte nuclei in blue; all cell borders are visualized in white. New ...

Using human induced pluripotent stem cells, researchers have built a miniature 3D liver model that replicates the critical interaction between hepatocytes and stellate cells. As chronic liver disease ...

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and ...