Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

To study living organisms at ever smaller length scales, scientists must devise new techniques to overcome the so-called diffraction limit. This is the intrinsic limitation on a microscope's ability ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Overcoming the resolution limit in a light microscope of around half a wavelength of light (about 250 nanometers) is one of the most significant developments in optics. Due to the wave nature of light ...

With the rapid revolution in super-resolution microscopy, the resolution of far-field optical microscopy has entered the sub-nanometer era, providing new insights into macromolecules in vitro and in ...

Understanding how cells are organized and how their molecular components interact in a coordinated and cooperative manner is a central goal of modern life sciences. To answer these questions, ...

In a study published in Science Advances, a team of bioengineering researchers at the University of Illinois Urbana-Champaign developed an algorithm known as adaptive intersection maximization, or AIM ...

A compact nanopositioning stage provides fast response and high scanning speed – ideal for fiber alignment and super resolution microscopy applications – new from PI. Auburn, MA – PI’s P-616 XYZ Piezo ...